High-sucrose-induced maternal obesity disrupts ovarian function and decreases fertility in Drosophila melanogaster - Rita T. Brookheart1 , Alison R. Swearingen, Christina A. Collins, Laura M. Cline, Jennifer G. Duncan⁎

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Using our Drosophila model of maternal obesity, we noted that HSD females are quantitatively smaller than LSD controls (Fig. 2A-B) and, as our group demonstrated previously, weigh less (39). This decreased size is also evident in the ovaries, whereby, HSD females had ovaries that were 28% smaller than their LSD counterparts (Fig. 2C). Moreover, this decrease in overall ovarian size positively correlated with a decrease in the number of mature (stage 14+) eggs (Fig. 2D).

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